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Before buying tapentadol 100mg online, speak with a licensed healthcare professional. According to established guidelines, tapentadol 100mg is given to treat acute pain that is severe enough to require an opioid analgesic when other treatments are ineffective. Tapentadol ER should be given orally twice a day, roughly every 12 hours, at a dose of 100–250 mg. For people with chronic non-cancer pain, the recommended daily limit of 90 mg morphine equivalents is comparable to 300 mg of tapentadol.